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PubMed , Scientific Reports , vol

GSH behaves as redox sensor at the DNA synthesis onset by maintaining nuclear architecture providing the appropriate redox environment for DNA replication and safeguarding DNA integrity (72) and is a key regulator of epigenetic events critical in cell proliferation regulation and cellular resistance to apoptosis (73)

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This leads people to take higher and higher doses in an attempt to see results, which is often where the risk of taking "too much" begins