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Description
Depending on conformation and use, some horses seem to be more predisposed to this condition

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It was originally suggested that inactivation of cytAspAT by -chloro-l-alanine is due to modification of a lysine residue by aminoacrylate (Morino et al., 1974)

The impact of metformin use on the outcomes of locally advanced breast cancer patients receiving neoadjuvant chemotherapy: An open-labelled randomized controlled trial
