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In summary, though a meta-analyses of 6 longitudinal studies supports frontal Glx reductions in the context of AP treatment, three new studies in FEP have failed to document frontal Glu reductions

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For all other topics, the terms TRPC OR TRPV OR TRPM OR TRPA1 OR TRPML OR TRPP were combined (AND) with a specific keyword related to the topic, as follows: Structure, functioning, exogenous/endogenous modulators, and signaling pathways: structure OR modulation OR signaling. Expression and functions in ocular structures: Retina and retinal OR optic nerve OR pigment epithelium. Ocular diseases: Macular degeneration. Diabetic retinopathy, retina, methylglyoxal, glaucoma, intraocular pressure, retina retinitis pigmentosa, rd10, rd1. For this review, we highlighted studies published in English in the last 5 years that brought new information to the subject up to publication