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Additionally, prolonged incubation in dark conditions resulted in an increased GSSG/GSH ratio, attributed once again to GGT inhibition by aggregated TB m A (Fig

On the other hand, a low ROS state shows an OXPHOS-dominated M2 metabolic mode, featured by efficient ETC and reduced ROS production, which is conducive to the maintenance of M2 polarization and facilitates anti-inflammatory and repair functions (90)

doi:10.1016/j.cccn.2005.05.023

Introduction Glycogen synthase kinase 3 (GSK3), a member of the mitogen-activated protein (MAP) kinase superfamily, has two highly conserved homologous isoforms, GSK 3 (51 kDa) and GSK 3 (47 kDa)