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Mice treated with Lactobacillus plantarum exhibited enhanced expression levels of genes related to bile acid synthesis and reverse cholesterol transport in the liver

While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

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