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[DOI] [PubMed] [Google Scholar] 34.Morina D., Sessevmez M., Sinani G., Mlazmolu L., Cevher E
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Many drugs enter the BBB primarily through the transcellular pathway, so we can determine the physiological functional integrity of the in vitro model by immunofluorescence techniques to detect the amount of several membrane inward and outward transport proteins, such as GLUT-1, the transferrin receptor or P-glycoprotein[208]
Furthermore, these two pathways are vital components of both the AD-related pathway-gene network and the natural product-gene-pathway networks
