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SAM is actively synthesized, and all of the enzymes involved in the methylation process are present, including the methionine synthase pathway that regenerates methionine from Hcy

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[DOI] [PubMed] [Google Scholar] Bailey J.A., Yavor A.M., Viggiano L., Misceo D., Horvath J.E., Archidiacono N., Schwartz S., Rocchi M., Eichler E.E