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The result of such interactions are mutations and inactivation of various metabolic pathways

The degenerative process itself may deplete these resident progenitor pools, impair essential EMT processes required for cell migration, or hinder the ability of migrated cells to reach their target locations [39]

Cardiovascular effects Chronic and acute lead poisoning has been documented to cause cardiac and vascular damages with possibly fatal consequences, including hypertension and circulatory disorders [35]