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However, many researchers still prefer "local administration" variables in their testing protocols to ensure maximum concentration at the specific tissue site

Sekhar RV (2021) GlyNAC supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, aging hallmarks, metabolic defects, muscle strength, cognitive decline, and body composition: implications for healthy aging

Wuertz et al

It really depends on what's missing
