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HEPATOTOXICITY Hepatobiliary disorders, including acute liver failure, jaundice abnormal hepatic function, hepatic steatosis, hepatitis, hepatotoxicity, hyperbilirubinemia and non-alcoholic fatty liver, have been reported in patients receiving infliximab products post-marketing

There needs to be an effort to specifically define normal bilirubin levels and develop a specific treatment for individuals who exhibit low levels of bilirubin (hypobilirubinemia)

The following protocols represent common clinical strategies, though individual optimization should involve healthcare provider guidance

68,69,525 Compared with combined therapies, they further reduce the risk of drug-drug interactions and simplify administration, making treatment safer, more effective, and more convenient for patients