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Behavioral assessments showed that mice in the EAS treatment group (45.5 mg/kg/day, administered for 20 days) exhibited significant improvements in motor function, including prolonged latency in the rotarod test and enhanced scores in the suspension test

without clinically evident complications, including ascites, variceal hemorrhage, hepatic encephalopathy and/ or jaundice) and a control group of healthy volunteers participating in a prior prospective case-control study on intestinal permeability were available for analyses of intestinal oxidative stress

any in-vivo experimentation by qualified researchers under appropriate ethics approval is the responsibility of the institution and the principal investigator