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Collectively, the results of this study illustrate that AOD9604 exerts distinct metabolic effects depending on the genetic background of the animal and the presence of functional 3-ARs

Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-navarrete JM, Fernandez-real JM, Pissios P, Fraenkel PG (2017) Nicotinamide N -methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes

Bioavailability comparisons illustrate the advantage clearly

Kypreos KE, Karagiannides I, Fotiadou EH, Karavia EA, Brinkmeier MS, Giakoumi SM, et al
