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Collectively, the results of this study illustrate that AOD9604 exerts distinct metabolic effects depending on the genetic background of the animal and the presence of functional 3-ARs

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Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-navarrete JM, Fernandez-real JM, Pissios P, Fraenkel PG (2017) Nicotinamide N -methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes

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Bioavailability comparisons illustrate the advantage clearly

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Kypreos KE, Karagiannides I, Fotiadou EH, Karavia EA, Brinkmeier MS, Giakoumi SM, et al

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