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(As a compromise, we will use the more common terms vaccine and vaccination in this review.) Despite the worldwide vaccination campaign and declaration by the World Health Organization (WHO) announcing the end of the COVID-19 global health emergency in May 2023, COVID-19 remains a significant concern: the disease persists as an ongoing global health challenge, with recurring outbreaks and disproportionate impacts on vulnerable populations

and in people age 85 and older, the incidence was 7.6% (76 of every 1,000 people)

In fact, since B12 deficiencies can lead to mood changes, proper supplementation often helps improve mood-related issues

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