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Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior
doi: 10.1038/nbt.3908
sod-3 , cpr-2 , ctl-1 , and dod-6 upregulated
Subcutaneous injection delivers 8095% of the dose into systemic circulation, while oral achieves only 515% due to gastric acid and enzymatic degradation in the GI tract
