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2013;8:e83813
However, it is now recognized that development and progression of AD is likely due to multiple etiologies, and there is increasing evidence implicating oxidative stress (OS) as an early event in the trajectory of MCI and AD [2, 18, 75]
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The glutathione peroxidase (GPx) mimetic activity of the selenides and the spirodiazaselenuranes indicates that the substituents attached to nitrogen atom have significant effect on the activity
