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For example, due to the poor solubility of ferroptosis inducer withaferin A in water, withaferin A can be formulated in the amphiphilic degradable pH-sensitive nanocarrier to improve the convenience of drug delivery and reduce drug toxicity (Hassannia et al., 2018)

Detection windows and testing sensitivities continue to improve

When the balance of prooxidant and antioxidant reactions is disrupted, ROS are overproduced, leading to oxidative stress that impairs the normal functions of cellular lipids, proteins, DNA, and RNA

10.3389/fphar.2023.1194869 Front