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Vitamin B-12 is a water-soluble B complex vitamin found naturally in a variety of foods, including meat, fish and dairy products
Arbor et al., 2019)
PMC9272494 USP General Chapter 797: Pharmaceutical Compounding Sterile Preparations
Given that the sulfate group is the key heparin mimetic moiety contributing to binding affinity, various polymers generally employed in the construction of scaffolds or hydrogels, such as alginate, chitosan, dextran, and cellulose, can be sulfated to enhance noncovalent interactions with BAPPs
