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Expert Opinion In contrast to the prior versions of this guideline, this update no longer divides treatments into first-line through sixth-line tiers

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This randomized controlled trial shows that mobile and outpatient unsedated TNE may be an effective alternative to standard endoscopy to screen for BE

A previous study has shown that PN exerts a more significant impact on quality of life and carries a higher risk of psychological disorders (e.g., anxiety and depression) than other pruritic dermatoses (4)
