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PPIs block gastric H+K+-ATPase, which is responsible for pumping H+ ions from within gastric parietal cells into the gastric lumen, where they interact with Cl ions to form HCl

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Inhaled corticosteroids, however, have been studied in patients with BE and a 2009 review by Kapur et al.45 identified six randomized clinical trials which enrolled 278 of 303 randomized adult patients

Here we have shown that human CBS oligomerises into filaments, adopting (at least) two distinct architectures, respectively, for the basal and activated states