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These substitutions protect against dipeptidyl peptidase-IV (DPP-IV) cleavage, the enzyme that destroys natural GHRH within minutes (Alba et al., J Med Chem 2006)

RohnIMarschallTAKroepflNJensenKBAschnerMTuckSet alSelenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans

Reapproved 2000, pp