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(2003) Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress

It also depends on how the patient responds to the initial therapy

Additionally, numbness, tingling, or muscle weakness can be inflicted by a range of inherited disorders, including Charcot-Marie-Tooth Disease (a defect that causes abnormalities in nerves within your limbs)

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