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While systemic dihexa half life remains one to two hours, CNS concentrations may persist for four to six hours because the peptide is delivered to the target site without requiring blood-brain barrier penetration

While glutathione is a naturally occurring molecule in the body, it can interact with the way some medications are processed by the liver

The data indicates that C57BL/6NTac mice are more vulnerable to cpz toxin challenge in comparison to C57BL/6J mice

Moreover, the authors also noted significant improvements in behavior and dopaminergic functions in PD rats, suggesting that intranasal delivery of OE-MSCs may be a promising and minimally invasive alternative in PD treatment [104]