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Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial

This evidence suggests a unique role of SP signaling in PN
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Simultaneously, the components of metabolic syndrome exacerbate oxidative stress by upregulating nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) isoforms, further damaging glomerular endothelial cells and podocytes
