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In addition to the detrimental effect on health and well-being, a substantial economic and societal impact ( e.g., healthcare expenses, property damage, motor vehicle accidents) is often associated with these addictive disorders, with AUD alone costing $249 billion [5]

For example, previous studies on farm animals indicated that the highest accumulation of clenbuterol and salbutamol is to be expected in pigmented tissues, such as eye and hair, which can be explained by their high melanin binding affinity, liposolubility, and pH gradient between blood and hair 40

But once a round of antibiotics had purged the normal flora, C
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