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glutathione adducts Proposed mechanisms for (GSH) interaction with photooxoA2E Proposed metabolism of MRL-A to
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10.1016/j.pain.2012.04.016 279 TofthagenC.TanayM.PerlmanA.StarrJ.AdvaniP.SheffieldK.et al (2022)

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Outside of polymorphism, decreased GSH synthesis occurs during aging, diabetes mellitus, fibrotic diseases (including cystic fibrosis and pulmonary fibrosis), endotoxemia, and several hepatic disorders such as cholestatic and alcoholic liver injury [13,15]