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It has been proposed that oxidative damage, a consequence of ROS, plays a role in the pathogenesisthe formation, process, and advancement of neurodegenerative diseases and disorders, cancer, diabetes, and aging (592)

doi: 10.1017/S0007114516001033 [DOI] [PubMed] [Google Scholar] 195.Zhang L, Zhu M, Liu X, Zhao Z, Han P, Lv L, et al

Complete or partial bladder removal is the standard treatment for stage T2 (muscle invasive) bladder cancer, since the presence of muscle invasion appears to be the best predictor of aggressive behaviour

This part matters because even something as simple as a vitamin shot isn't always symptom-free