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Cardiovasc Res
Korneychuk, N
We observed a parallel liver-specific upregulation of Tfrc, which is the predominant transcript containing an iron response element (IRE) in the 3 UTR, indicating activation of the iron starvation response exclusively in the liver, known to be the site of systemic iron regulation (Fig 1G)
Unlike other forms of cell death such as iron death and apoptosis, copperinduced cell death has gained increasing recognition as a significant process influencing the development of cardiovascular diseases
