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Tozadenant showed positive effect on reducing OFF-time duration in a phase IIb, double-blind randomized trial (Hauser et al
Venugopal S, Issa G, Konopleva M, DiNardo C, Borthakur G , Jabbour E, Pemmaraju N, Yilmaz M, Short N, Maiti A, Sasaki K, Masarova L, Pierce S, Takahashi K, Tang G, Loghavi S, Andreeff M, Bhalla K, Garcia-Manero G, Ravandi F, Kantarjian H, Daver N
Growing attention was subsequently paid to the details of glutathione synthesis, degradation, transport and compartmentation (Rennenberg, 1982
