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CB1R mostly resides in the central nervous system (CNS) while the CB2R receptors are mostly expressed in the immune cells such as natural killer cells, neutrophils, and monocytes as well as other tissues such as the bladder, intestine, etc

In the newborn, an erythrocyte isozyme of the M-type with comparatively low PK activity displaces the fetal type, resulting in an accumulation of glycolytic intermediates

doi: 10.1016/j.cell.2017.09.021 179 ZhaoYLiYZhangRWangFWangTJiaoY

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