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However, the gap between laboratory findings and human clinical evidence remains substantial

Most patients with type I congenital methemoglobinemia are asymptomatic except for cyanosis (only of cosmetic significance), but some forms may have serious morbidity (some patients might experience headache, exertional dyspnea, and fatigue)

2025 27;e10483

In an attempt to reduce excessive oxidative stress in sickle red cells another compound gained interest: L-glutamine
