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Description
Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

and (+++) total score 5 points, in which () or (+) form the low-expression groups, whereas (++) and (+++) are the high-expression groups

Open label trial of coenzyme Q10 as a migraine preventive

Nat Rev Cancer 19:405414