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Elevated levels of MNAM were detected in the urine (Li et al., 2018) and serum (Souto et al., 2005) demonstrated an upregulation of NNMT expression in the WAT of individuals with IR or T2D

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Results from this study suggest that hepatic fat export in periparturient dairy cows is improved by choline supplementation during the transition period and this may potentially decrease the risk for metabolic disorders in the periparturient dairy cow. [7] Choline is also known to be involved in the synthesis of carnitine, cell membrane phospholipids, and the neurotransmitter acetylcholine