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Biology, genetics, and environment: Underlying factors influencing alcohol metabolism

Catabolic metabolites (e.g., -keto acids and aldehydes) of branched-chain amino acids (leucine and isoleucine) can further react with reducing sugars or fatty acids to generate compounds with distinctive flavor profiles (32, 46)

Safety Measurements Any adverse event during the course of the study was monitored and reported to the study staff at week 6 (visit 5) or week 12 (visit 8) in the clinic or directly to the principal investigator throughout the study