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Glutathione peroxidase (GPx) is found in all cells and uses GSH for detoxification of hydrogen peroxide and organic (lipid) peroxides in the cytosol and cell membranes (see Fig
doi: 10.1038/nchembio.2239 322 ChenYLiLLanJCuiYRaoXZhaoJet al
it is typically unilateral at onset, becoming bilateral as the disease progresses
