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Moreover, activation of PKC with phorbol ester is known to induce 1A -AR phosphorylation, indicating heterologous desensitization, albeit to a much lesser extent than 1B -AR (Vzquez-Prado et al., 2000)

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After 1 h, crystals were cryoprotected by addition of 10% ethylene glycol to the drops before crystal harvesting and flash-freezing in liquid nitrogen

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