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The anti-inflammatory activity, capsaicin-induced somatosensory neurons damage counteraction [21], recovery of sciatic nerve after transection [22], and cultured enteric neurons and glial cells protection [23] have been all reported

Overall, the information garnered from kratom-associated polyintoxications and the in vitro inhibitory effects of kratom (and its alkaloids) on P450 and P-gp activity suggests a high likelihood of observing additional pharmacokinetic kratom-drug interactions that affect drug pharmacodynamics

It has gained attention for its impressive ability to support the healing of skin, muscle, bone, ligaments and tendons in many animal studies