kegg pathway glutathione metabolism metabolic pathways. GCL, glutamate cysteine ligase; GST, A mathematical model of glutathione

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3.4.2 Cytokines/chemokines/transcription factors BTZ markedly upregulates TNF- expression in DRG neurons, activates TNFR1 and TNFR2 co-receptors, sensitizes nociceptive neurons, and mediates mechanical allodynia (Zhang et al., 2014)