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However, on the TNF flow cell surface, all dosed subjects in cohort 7 showed increasing signal compared to baseline which was confirmed with the anti-human IgG reagent, but not the AMG 966-specific antibody 1A3, indicating these subjects developed endogenous anti-TNF antibodies as a result of AMG 966 treatment ( Figures 8F, H )
US Federal Register
Association of TNF, TNFR1, and TNFR2 polymorphisms with sperm concentration and motility
CTL, Cytotoxic T Lymphocytes
