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Nevertheless, challenges associated with BMP-2 include its short half-life, complex production equipment and preparation process, as well as supraphysiological doses, which may lead to side effects such as inflammation, pain, heterotopic ossification, or even osteolysis [403]

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It is well known that in areas with severe and chronic iodine insufficiency, hypothyroidism can occur in both mothers and fetuses from the early stages of gestation, leading to irreversible brain damage, mental retardation, and neurological abnormalities [11,12]

Healthy Diet : Eat foods rich in antioxidants Good Sleep : Skin repairs itself during sleep Stay Hydrated : Drink plenty of water Complement With Professional Care Consider combining home use with professional treatments like chemical peels or rejuvenating facials for enhanced results