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The time to develop this scar and the degree to which it occurs varies from patient to patient
Eur Heart J (2016) 37:172332
24 Older adults are particularly vulnerable due to age-related decreases in stomach acid production, with B12 deficiency prevalence reaching 6% in those 60 years and 20% in those 85 years
Research protocols employ diverse approaches including isolated mitochondria preparations, permeabilized muscle fiber respirometry, stable isotope tracers for metabolic flux analysis, cellular bioenergetics assays (Seahorse), and in vivo metabolic phenotyping in rodent models
