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Pathophysiology beyond dopaminergic neuronal loss The alpha-synuclein model Alpha-synuclein is a presynaptic neuronal protein whose abnormal aggregation into Lewy bodies leads to disruption in cellular homeostasis and consequently neurodegeneration 7

29 Bioavailability of IGFs is regulated by a class of six IGF-binding proteins (IGFBP-16), which are also produced in the liver

medRxiv 2020.05.13.20087734

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