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In humans, methylcobalamin functions in the folate-dependent methylation of homocysteine to methionine (Figure 22b.2) whereas 5'deoxyadenosyl-cobalamin plays a major part in the conversion of Lmethylmalonyl-coenzyme A to succinyl-coenzyme A in an isomerization reaction
Piriformis syndrome can be painful, but it is seldom dangerous and rarely leads to the need for surgery
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