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The pentose phosphate pathway (PPP) is a glucose-oxidizing pathway that runs in parallel to upper glycolysis to produce ribose 5-phosphate and nicotinamide adenine dinucleotide phosphate (NADPH)

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In pregnancy, excessive inflammation is associated with major pregnancy-related complications such as preterm labor, placental thrombosis, placenta insufficiency, and developmental delays in neonates exposed to excessive inflammation before birth