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As a result of high epithelial oxygen consumption, the epithelial surface is kept in a hypoxic state, favoring a microbiota dominated by obligate anaerobic bacteria

Ives CW, Sinkey R, Rajapreyar I, Tita ATN, Oparil S (2020) Preeclampsia-pathophysiology and clinical presentations: JACC state-of-the-art review
The nephrotoxin ochratoxin A induces key parameters of chronic interstitial nephropathy in renal proximal tubular cells

After injecting bacterial amyloids into the wall of the stomach of mice, aggregates of fluorescent mouse beta-amyloid were found within hours in the enteric nervous system, within a month elsewhere in the gut as well, and within a year in the vagus nerve and brain, including the hippocampus (Sun et al., 2020a)
