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Moreover, rats treated with 1% neohesperidin dihydrochalcone for 1 month showed reduced amygdala neuroinflammation via suppression of cAMP/PKA pathway activity, restoration of cortical 5-HT, DA, and NE levels, and reversal of anxiety- and depression-like behaviors (Jiang et al., 2023)

Notably, 50% of measured NADP + in frozen blood originated from NADPH, allowing for extrapolation of NADPH and NADP + levels before freezing, if fresh sample analysis is not feasible

Public Health Service Policy on Humane Care and Use of Laboratory Animals and the Guide for the Care and Use of Laboratory Animals (National Research Council, 8th edition, 2011)

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