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To investigate whether the increase in GSH level at 600 g/ml D-HIS was stable during long-term cultivation, GSH content was monitored during sequential batch cultivation up to 60 generations
67 Tirzepatide initiation dose was 2.5 mg once weekly and increased by 2.5 mg every 4 weeks until reaching the target dose (a lower starting dose and a slower escalation regime compared to the phase 2 trial)
"The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli"
