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Notably, cortisol levels were significantly elevated in the DN group and were associated with steroid hormone biosynthesis pathway enrichment
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DOI: 10.1111/jipb.13799 Editorial Office, Journal of Integrative Plant Biology, Institute of Botany, CAS No
Among the proteins hyperacetylated upon SLC25A51 KO were pyrroline-5-carboxylate reductase 1 (PYCR1) and Delta-1-pyrroline-5-carboxylate synthase (P5CS), which are tandem enzymes involved in proline synthesis from glutamate, leading to P5CS inhibition and proline depletion [198]
