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Apparently, the type 1 SECIS found in GPx-1 interacts with eIF4a3, a factor that is induced in selenium deficiency

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demonstrated that crocodilian oil significantly reduced both synthesis and gene expression of interleukin-6 (IL-6), and inhibited the expression of key pro-inflammatory mediators, including cyclooxygenase-2, prostaglandin E2, nitric oxide (NO), and NF-B, in lipopolysaccharide-stimulated RAW 264.7 macrophages

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