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Furthermore, curcumin administration significantly attenuates mitochondrial swelling, reduces lipid peroxidation and protein carbonyl formation, and decreases ROS production in HD rats (Sandhir et al., 2014)

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Ongoing clinical trials are exploring other applications of CD38 antibody containing IgA nephropathy (NCT05065970) and even metastatic renal cell carcinoma (NCT03473730).The study( NCT05704400 )is researching the effectiveness of the combination therapy of CD20 monoclonal antibody and daratumumab monoclonal antibody in the treatment of pediatric multidrug-resistant nephrotic syndrome ( Table 2 )

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