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[PubMed] [Google Scholar] 24.Rodbell M, Birnbaumer L, Pohl SL, Krans HM

Macroautophagy requires autophagosome formation to pack abnormal proteins and organelles into autophagosomes and fusion with lysosomes to digest the contents [8]
Metal-mediated immune regulations and interventions: prospects of the emerging field of metalloimmunology

In summary, development defects in the CNS in GDH-HI patients could be caused by multiple factors, including chronic hyperammonemia, and hyperinsulinemia, the more detailed mechanisms need to be further studied
